Standard

Creatinine levels

PRKAG2 · rs78573217

Where this position leads

Conditions: Kidney Function, Gout

rs78573217 Condition: Kidney Function Kidney Function Condition Condition: Gout Gout Condition rs78573217 rs78573217 PRKAG2

What the study found

Who was studied 342,376 European ancestry individuals, 6,016 African ancestry individuals, 7,339 South Asian ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.0562 higher (95% confidence interval 0.044-0.068); p = 7 × 10−21.

Where it sits Chromosome 7, band 7q36.1 — in an intron of PRKAG2.

What each result means

A/A Two copies of the version the research linked to Creatinine levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/C One copy of the version the research linked to Creatinine levels. That is a smaller link than two copies.
C/C No copy of the version the research linked to Creatinine levels. This is the starting point the study compared everyone against.
Source

Questions about rs78573217

What is rs78573217?

rs78573217 is a single position in the genome, in or near the PRKAG2 gene. Published research associates it with creatinine levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs78573217 linked to?

On MyGeneLog this position is linked to Kidney Function, Gout. The research behind each link, and its sources, are set out on that condition page.

Does having rs78573217 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs78573217 come from?

GWAS Catalog, Nature genetics 2021, PMID:33462484. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Creatinine levels (rs78573217). MyGeneLog™. https://www.mygenelog.com/variants/rs78573217

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