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D-dimer levels in HIV infection

CATSPERG · rs78474816

Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.

What the study found

Who was studied 4,675 European ancestry individuals, 1,732 African ancestry individuals, 645 Admixed American individuals.

The effect Each copy of the T allele shifted the measure 1.38 higher (95% confidence interval 0.99-1.77); p = 4 × 10⁻¹².

Where it sits Chromosome 19, band 19q13.2 — in an intron of CATSPERG.

What each result means

C/C No copy of the version the research linked to D-dimer levels in HIV infection. This is the starting point the study compared everyone against.

C/T One copy of the version the research linked to D-dimer levels in HIV infection. That is a smaller link than two copies.

T/T Two copies of the version the research linked to D-dimer levels in HIV infection. That is the strongest link of the three results. A link in a study is not a diagnosis.

Source

Genome-wide association study of high-sensitivity C-reactive protein, D-dimer, and interleukin-6 levels in multiethnic HIV+ cohorts

Sherman BT, Hu X, Singh K, Haine L, Rupert AW, Neaton JD, Lundgren JD, Imamichi T, Chang W, Lane HC

ESPRIT, SMART and START Study Groups

AIDS (London, England) · 2021 · PMID 33095540 · open access

Questions about rs78474816

What is rs78474816?

rs78474816 is a single position in the genome, in or near the CATSPERG gene. Published research associates it with d-dimer levels in hiv infection. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs78474816 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs78474816 come from?

GWAS Catalog, AIDS (London, England) 2021, PMID:33095540. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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D-dimer levels in HIV infection (rs78474816). MyGeneLog™. https://www.mygenelog.com/variants/rs78474816

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