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Intracranial aneurysm

LINC01237 · rs78458145

Where this position leads

Condition: Intracranial Aneurysm

rs78458145 Condition: Intracranial Aneurysm Intracranial Aneurysm Condition rs78458145 rs78458145 LINC01237

What the study found

Who was studied 250 Korean ancestry cases, 296 Korean ancestry controls.

The effect Each copy of the G allele carried 4.17 times the odds of Intracranial aneurysm (95% confidence interval 2.86-5.88); p = 3 × 10−15.

How common The G allele had a frequency of about 60% in the people studied.

Where it sits Chromosome 2, band 2q37.3 — in an intron of LINC01237.

What each result means

A/A Published research associates this genotype with typical/baseline likelihood of Intracranial aneurysm — no copies of the reported risk allele.
A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Intracranial aneurysm.
G/G Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Intracranial aneurysm compared to the general population.
Source

Questions about rs78458145

What is rs78458145?

rs78458145 is a single position in the genome, in or near the LINC01237 gene. Published research associates it with intracranial aneurysm. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs78458145 linked to?

On MyGeneLog this position is linked to Intracranial Aneurysm. The research behind each link, and its sources, are set out on that condition page.

Does having rs78458145 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs78458145 come from?

GWAS Catalog, Journal of clinical medicine 2019, PMID:30823506. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Intracranial aneurysm (rs78458145). MyGeneLog™. https://www.mygenelog.com/variants/rs78458145

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