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Male-pattern baldness

LAX1 · rs78448052

What the study found

Who was studied 52,874 British ancestry males.

The effect Each copy of the T allele shifted the measure 0.143 lower; p = 1 × 10−15.

Where it sits Chromosome 1, band 1q32.1 — between genes, 36.2 kb from LINC00303.

What each result means

C/C No copy of the version the research linked to Male-pattern baldness. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Male-pattern baldness. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Male-pattern baldness. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs78448052

What is rs78448052?

rs78448052 is a single position in the genome, in or near the LAX1 gene. Published research associates it with male-pattern baldness. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs78448052 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs78448052 come from?

GWAS Catalog, PLoS genetics 2017, PMID:28196072. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Male-pattern baldness (rs78448052). MyGeneLog™. https://www.mygenelog.com/variants/rs78448052

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