Standard

Diastolic blood pressure

SLC25A37 · rs7842144

Where this position leads

Condition: Blood Pressure

rs7842144 Condition: Blood Pressure Blood Pressure Condition rs7842144 rs7842144 SLC25A37

What the study found

Who was studied 340,162 European ancestry individuals, 145,515 East Asian ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.0142 higher (95% confidence interval 0.0099-0.0185); p = 2 × 10−10.

Where it sits Chromosome 8, band 8p21.2 — in an intron of SLC25A37.

What each result means

G/G Two copies of the version the research linked to Diastolic blood pressure. That is the strongest link of the three results. A link in a study is not a diagnosis.
G/T One copy of the version the research linked to Diastolic blood pressure. That is a smaller link than two copies.
T/T No copy of the version the research linked to Diastolic blood pressure. This is the starting point the study compared everyone against.
Source

Questions about rs7842144

What is rs7842144?

rs7842144 is a single position in the genome, in or near the SLC25A37 gene. Published research associates it with diastolic blood pressure. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs7842144 linked to?

On MyGeneLog this position is linked to Blood Pressure. The research behind each link, and its sources, are set out on that condition page.

Does having rs7842144 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs7842144 come from?

GWAS Catalog, Nature genetics 2021, PMID:34594039. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Diastolic blood pressure (rs7842144). MyGeneLog™. https://www.mygenelog.com/variants/rs7842144

← See all variants