Standard

Aspartate aminotransferase levels

near ZNF704 · rs7840329

Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.

What the study found

Who was studied 507,850 East Asian ancestry individuals, 420,829 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.01 higher (95% confidence interval 0.0069-0.0131); p = 2 × 10⁻¹⁰.

Where it sits Chromosome 8, band 8q21.13 — between genes, 15.8 kb from ZNF704.

What each result means

A/A Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Aspartate aminotransferase levels compared to the general population.

A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Aspartate aminotransferase levels.

G/G Published research associates this genotype with typical/baseline likelihood of Aspartate aminotransferase levels — no copies of the reported risk allele.

Source

Genome-wide association studies in a large Korean cohort identify quantitative trait loci for 36 traits and illuminate their genetic architectures

Jee YH, Wang Y, Jung KJ, Lee JY, Kimm H, Duan R, Price AL, Martin AR, Kraft P

Nature communications · 2025 · PMID 40436827 · open access

Questions about rs7840329

What is rs7840329?

rs7840329 is a single position in the genome, in or near the near ZNF704 gene. Published research associates it with aspartate aminotransferase levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs7840329 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs7840329 come from?

GWAS Catalog, Nature communications 2025, PMID:40436827. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Aspartate aminotransferase levels (rs7840329). MyGeneLog™. https://www.mygenelog.com/variants/rs7840329

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