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Bone mineral density (hip)

TNFRSF11B · rs7839059

What the study found

Who was studied 6,912 European ancestry individuals; replicated in 845 African American individuals, 446 Hispanic individuals, 971 European ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.1 lower; p = 7 × 10−9.

Where it sits Chromosome 8, band 8q24.12 — inside COLEC10.

What each result means

A/A No copy of the version the research linked to Bone mineral density (hip). This is the starting point the study compared everyone against.
A/C One copy of the version the research linked to Bone mineral density (hip). That is a smaller link than two copies.
C/C Two copies of the version the research linked to Bone mineral density (hip). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs7839059

What is rs7839059?

rs7839059 is a single position in the genome, in or near the TNFRSF11B gene. Published research associates it with bone mineral density (hip). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs7839059 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs7839059 come from?

GWAS Catalog, Osteoporos Int 2016, PMID:27311723. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Bone mineral density (hip) (rs7839059). MyGeneLog™. https://www.mygenelog.com/variants/rs7839059

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