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Pulse pressure

HIVEP3 · rs783622

Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.

What the study found

Who was studied 322,141 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 6.36 z score higher; p = 2 × 10⁻¹⁰.

Where it sits Chromosome 1, band 1p34.2 — in an intron of HIVEP3.

What each result means

A/A Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Pulse pressure compared to the general population.

A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Pulse pressure.

G/G Published research associates this genotype with typical/baseline likelihood of Pulse pressure — no copies of the reported risk allele.

Source

Large-scale brainstem neuroimaging and genetic analyses provide new insights into the neuronal mechanisms of hypertension

Gurholt TP, Elvsåshagen T, Bahrami S, Rahman Z, Shadrin A, Askeland-Gjerde DE, van der Meer D, Frei O, Kaufmann T, Sønderby IE, Halvorsen S, Westlye LT

and 1 more — show all

Andreassen OA

HGG advances · 2025 · PMID 39663699 · open access

Questions about rs783622

What is rs783622?

rs783622 is a single position in the genome, in or near the HIVEP3 gene. Published research associates it with pulse pressure. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs783622 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs783622 come from?

GWAS Catalog, HGG advances 2025, PMID:39663699. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Pulse pressure (rs783622). MyGeneLog™. https://www.mygenelog.com/variants/rs783622

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