Mean platelet volume during third trimester of pregnancy
NOS1AP · rs78344479
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Who was studied 71,605 Chinese ancestry individuals.
The effect
Each copy of the T allele shifted the measure 0.0487 higher (95% confidence interval 0.033-0.064); p = 3 × 10−10.
How common The T allele had a frequency of about 23% in the people studied.
Where it sits Chromosome 1, band 1q23.3 — in an intron of NOS1AP.
What each result means
G/GNo copy of the version the research linked to Mean platelet volume during third trimester of pregnancy. This is the starting point the study compared everyone against.
G/TOne copy of the version the research linked to Mean platelet volume during third trimester of pregnancy. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Mean platelet volume during third trimester of pregnancy. That is the strongest link of the three results. A link in a study is not a diagnosis.
rs78344479 is a single position in the genome, in or near the NOS1AP gene. Published research associates it with mean platelet volume during third trimester of pregnancy. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does rs78344479 affect how medicines work?
NOS1AP carries pharmacogenomic findings for QT-prolonging medicines. That is educational information, not a prescription or a dosing guide. Any decision to start, stop or change a medicine belongs with the clinician or pharmacist managing your treatment.
Does having rs78344479 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs78344479 come from?
GWAS Catalog, Blood 2024, PMID:38064665. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Quoting this page
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Mean platelet volume during third trimester of pregnancy (rs78344479). MyGeneLog™. https://www.mygenelog.com/variants/rs78344479