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Medication use (beta blocking agents)

ZNF831 · rs78302204

Where this position leads

Condition: Medication Use as a Genetic Trait

rs78302204 Condition: Medication Use as a Genetic Trait Medication Use as a Genetic Trait Condition rs78302204 rs78302204 ZNF831

What the study found

Who was studied 31,700 European ancestry cases, 192,324 European ancestry controls.

The effect Each copy of the A allele shifted the measure 0.0956 higher (95% confidence interval 0.069-0.122); p = 1 × 10−12.

How common The A allele had a frequency of about 11% in the people studied.

Where it sits Chromosome 20, band 20q13.32 — in the 5′ untranslated region of ZNF831.

What each result means

A/A Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Medication use (beta blocking agents) compared to the general population.
A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Medication use (beta blocking agents).
G/G Published research associates this genotype with typical/baseline likelihood of Medication use (beta blocking agents) — no copies of the reported risk allele.
Source

Questions about rs78302204

What is rs78302204?

rs78302204 is a single position in the genome, in or near the ZNF831 gene. Published research associates it with medication use (beta blocking agents). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs78302204 linked to?

On MyGeneLog this position is linked to Medication Use as a Genetic Trait. The research behind each link, and its sources, are set out on that condition page.

Does having rs78302204 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs78302204 come from?

GWAS Catalog, Nat Commun 2019, PMID:31015401. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Medication use (beta blocking agents) (rs78302204). MyGeneLog™. https://www.mygenelog.com/variants/rs78302204

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