1 1612238Reads by AI crawlersClaude1ChatGPT0Google · Gemini2Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple3Others8Total16Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 426,824 British ancestry individuals.
The effect
Each copy of the C allele shifted the measure 0.0375 lower (95% confidence interval 0.026-0.049); p = 2 × 10−10.
How common The C allele had a frequency of about 97% in the people studied.
Where it sits Chromosome 1, band 1p31.3 — in an intron of GNG12-AS1.
What each result means
C/CPublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Heel bone mineral density compared to the general population.
C/TPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Heel bone mineral density.
T/TPublished research associates this genotype with typical/baseline likelihood of Heel bone mineral density — no copies of the reported risk allele.
Nature genetics · 2019 · PMID 30598549 · open access
Questions about rs78252812
What is rs78252812?
rs78252812 is a single position in the genome, in or near the GNG12-AS1 gene. Published research associates it with heel bone mineral density. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs78252812 linked to?
On MyGeneLog this position is linked to Heel Bone Mineral Density. The research behind each link, and its sources, are set out on that condition page.
Does having rs78252812 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs78252812 come from?
GWAS Catalog, Nat Genet 2018, PMID:30598549. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
1 1612238Reads by AI crawlersClaude1ChatGPT0Google · Gemini2Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple3Others8Total16Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Heel bone mineral density (rs78252812). MyGeneLog™. https://www.mygenelog.com/variants/rs78252812