Sensitive
Depression
near NEGR1 · rs782212
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What each result means
C/C
Published research associates this genotype with typical/baseline likelihood of Depression — no copies of the reported risk allele.
C/T
Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Depression.
T/T
Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Depression compared to the general population.
Source
Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses
Okbay A,
Baselmans BM,
De Neve JE,
Turley P,
Nivard MG,
Fontana MA,
Meddens SF,
Linnér RK,
Rietveld CA,
Derringer J,
Gratten J,
Lee JJ
and 180 more — show all
Liu JZ,
de Vlaming R,
Ahluwalia TS,
Buchwald J,
Cavadino A,
Frazier-Wood AC,
Furlotte NA,
Garfield V,
Geisel MH,
Gonzalez JR,
Haitjema S,
Karlsson R,
van der Laan SW,
Ladwig KH,
Lahti J,
van der Lee SJ,
Lind PA,
Liu T,
Matteson L,
Mihailov E,
Miller MB,
Minica CC,
Nolte IM,
Mook-Kanamori D,
van der Most PJ,
Oldmeadow C,
Qian Y,
Raitakari O,
Rawal R,
Realo A,
Rueedi R,
Schmidt B,
Smith AV,
Stergiakouli E,
Tanaka T,
Taylor K,
Thorleifsson G,
Wedenoja J,
Wellmann J,
Westra HJ,
Willems SM,
Zhao W,
Amin N,
Bakshi A,
Bergmann S,
Bjornsdottir G,
Boyle PA,
Cherney S,
Cox SR,
Davies G,
Davis OS,
Ding J,
Direk N,
Eibich P,
Eibich P,
Emeny RT,
Fatemifar G,
Faul JD,
Ferrucci L,
Ferrucci L,
Forstner AJ,
Gieger C,
Gupta R,
Harris TB,
Harris JM,
Holliday EG,
Hottenga JJ,
De Jager PL,
Kaakinen MA,
Kajantie E,
Karhunen V,
Kolcic I,
Kumari M,
Launer LJ,
Franke L,
Franke L,
Li-Gao R,
Liewald DC,
Koini M,
Loukola A,
Marques-Vidal P,
Montgomery GW,
Mosing MA,
Paternoster L,
Pattie A,
Petrovic KE,
Pulkki-Råback L,
Quaye L,
Räikkönen K,
Rudan I,
Scott RJ,
Smith JA,
Sutin AR,
Trzaskowski M,
Vinkhuyzen AE,
Yu L,
Zabaneh D,
Attia JR,
Bennett DA,
Berger K,
Bertram L,
Boomsma DI,
Snieder H,
Chang SC,
Cucca F,
Deary IJ,
van Duijn CM,
Eriksson JG,
Bültmann U,
de Geus EJ,
Groenen PJ,
Gudnason V,
Hansen T,
Hartman CA,
Haworth CM,
Haworth CM,
Hayward C,
Heath AC,
Hinds DA,
Hyppönen E,
Iacono WG,
Järvelin MR,
Jöckel KH,
Kaprio J,
Kardia SL,
Keltikangas-Järvinen L,
Kraft P,
Kubzansky LD,
Lehtimäki T,
Magnusson PK,
Martin NG,
McGue M,
Metspalu A,
Mills M,
de Mutsert R,
Oldehinkel AJ,
Pasterkamp G,
Pedersen NL,
Plomin R,
Polasek O,
Power C,
Rich SS,
Rosendaal FR,
den Ruijter HM,
Schlessinger D,
Schmidt H,
Svento R,
Schmidt R,
Alizadeh BZ,
Sørensen TI,
Spector TD,
Starr JM,
Stefansson K,
Steptoe A,
Terracciano A,
Thorsteinsdottir U,
Thurik AR,
Timpson NJ,
Tiemeier H,
Uitterlinden AG,
Vollenweider P,
Vollenweider P,
Wagner GG,
Weir DR,
Yang J,
Conley DC,
Smith GD,
Hofman A,
Johannesson M,
Laibson DI,
Medland SE,
Meyer MN,
Pickrell JK,
Esko T,
Krueger RF,
Beauchamp JP,
Koellinger PD,
Benjamin DJ,
Bartels M,
Cesarini D
Nature genetics · 2016 · PMID 27089181 · open access
Questions about rs782212
What is rs782212?
rs782212 is a single position in the genome, in or near the near NEGR1 gene. Published research associates it with depression. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs782212 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs782212 come from?
GWAS Catalog, Nat Genet 2016, PMID:27089181. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
← See all variants