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Immunoglobulin light chain (AL) amyloidosis (liver involvement)

FAM150A · rs7820212

Where this position leads

Condition: Immunoglobulin Light Chain (AL) Amyloidosis

rs7820212 Condition: Immunoglobulin Light Chain (AL) Amyloidosis Immunoglobulin Light Chain (AL) Amy… Condition rs7820212 rs7820212 FAM150A

What the study found

Who was studied 194 cases, controls.

The effect Each copy of the A allele carried 1.86 times the odds of Immunoglobulin light chain (AL) amyloidosis (liver involvement) (95% confidence interval 1.50-2.31); p = 2 × 10−8.

Where it sits Chromosome 8, band 8q11.23 — between genes, 27.8 kb from ALKAL1.

What each result means

A/A Two copies of the version the research linked to Immunoglobulin light chain (AL) amyloidosis (liver involvement). That is the strongest link of the three results. A link in a study is not a diagnosis.
A/T One copy of the version the research linked to Immunoglobulin light chain (AL) amyloidosis (liver involvement). That is a smaller link than two copies.
T/T No copy of the version the research linked to Immunoglobulin light chain (AL) amyloidosis (liver involvement). This is the starting point the study compared everyone against.
Source

Questions about rs7820212

What is rs7820212?

rs7820212 is a single position in the genome, in or near the FAM150A gene. Published research associates it with immunoglobulin light chain (al) amyloidosis (liver involvement). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs7820212 linked to?

On MyGeneLog this position is linked to Immunoglobulin Light Chain (AL) Amyloidosis. The research behind each link, and its sources, are set out on that condition page.

Does having rs7820212 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs7820212 come from?

GWAS Catalog, Haematologica 2017, PMID:28679651. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Immunoglobulin light chain (AL) amyloidosis (liver involvement) (rs7820212). MyGeneLog™. https://www.mygenelog.com/variants/rs7820212

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