Standard

Vitamin D levels

CALCB · rs78110496

Where this position leads

Condition: Gout

rs78110496 Condition: Gout Gout Condition rs78110496 rs78110496 CALCB

What the study found

Who was studied 327,435 European ancestry individuals, 5,845 African ancestry individuals, 6,425 South Asian ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.0663 lower (95% confidence interval 0.057-0.076); p = 7 × 10−43.

Where it sits Chromosome 11, band 11p15.2 — inside CALCB.

What each result means

A/A No copy of the version the research linked to Vitamin D levels. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Vitamin D levels. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Vitamin D levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs78110496

What is rs78110496?

rs78110496 is a single position in the genome, in or near the CALCB gene. Published research associates it with vitamin d levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs78110496 linked to?

On MyGeneLog this position is linked to Gout. The research behind each link, and its sources, are set out on that condition page.

Does having rs78110496 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs78110496 come from?

GWAS Catalog, Nat Genet 2021, PMID:33462484. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Vitamin D levels (rs78110496). MyGeneLog™. https://www.mygenelog.com/variants/rs78110496

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