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Insulin-like growth factor 1 levels

FAM120A · rs78108956

Where this position leads

Condition: Gout

rs78108956 Condition: Gout Gout Condition rs78108956 rs78108956 FAM120A

What the study found

Who was studied 340,567 European ancestry individuals, 5,974 African ancestry individuals, 7,283 South Asian ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.0333 higher (95% confidence interval 0.022-0.044); p = 5 × 10−9.

Where it sits Chromosome 9, band 9q22.31 — in an intron of FAM120A.

What each result means

C/C No copy of the version the research linked to Insulin-like growth factor 1 levels. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Insulin-like growth factor 1 levels. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Insulin-like growth factor 1 levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs78108956

What is rs78108956?

rs78108956 is a single position in the genome, in or near the FAM120A gene. Published research associates it with insulin-like growth factor 1 levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs78108956 linked to?

On MyGeneLog this position is linked to Gout. The research behind each link, and its sources, are set out on that condition page.

Does having rs78108956 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs78108956 come from?

GWAS Catalog, Nature genetics 2021, PMID:33462484. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Insulin-like growth factor 1 levels (rs78108956). MyGeneLog™. https://www.mygenelog.com/variants/rs78108956

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