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Red blood cell count

NUP205 · rs7810260

Where this position leads

Condition: Blood Cell Counts

rs7810260 Condition: Blood Cell Counts Blood Cell Counts Condition rs7810260 rs7810260 NUP205

What the study found

Who was studied 408,112 British individuals.

The effect Each copy of the A allele shifted the measure 0.0142 lower (95% confidence interval 0.0099-0.0185); p = 1 × 10−10.

How common The A allele had a frequency of about 51% in the people studied.

Where it sits Chromosome 7, band 7q33 — in an intron of NUP205.

What ClinVar records

Classification Benign for Nephrotic syndrome, type 13; criteria provided, multiple submitters, no conflicts (2 of 4 stars, 5 submitters), last evaluated 2026-02-02. ClinVar record 1278454 NM_015135.3(NUP205):c.4793+11G>A

What this is ClinVar's aggregate record for this position (as of its 2026-10-12 release), not a result about you. A classification describes the variant against the condition named, as laboratories submitted it. Whether a person carries this variant, and what that would mean for them, is a question for a clinical test and a genetic counsellor.

What each result means

A/A Two copies of the version the research linked to Red blood cell count. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Red blood cell count. That is a smaller link than two copies.
G/G No copy of the version the research linked to Red blood cell count. This is the starting point the study compared everyone against.
Source

Questions about rs7810260

What is rs7810260?

rs7810260 is a single position in the genome, in or near the NUP205 gene. Published research associates it with red blood cell count. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs7810260 linked to?

On MyGeneLog this position is linked to Blood Cell Counts. The research behind each link, and its sources, are set out on that condition page.

Does having rs7810260 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs7810260 come from?

GWAS Catalog, Cell 2020, PMID:32888494. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Red blood cell count (rs7810260). MyGeneLog™. https://www.mygenelog.com/variants/rs7810260

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