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Androsterone sulfate-to-4-androsten-3beta,17beta-diol disulfate 2 ratio

near ZNF655 · rs7809615

What the study found

Who was studied 5,555 European ancestry individuals; replicated in 1,753 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.249 lower (95% confidence interval -0.23--0.27); p = 8 × 10−139.

How common The T allele had a frequency of about 9% in the people studied.

Where it sits Chromosome 7, band 7q22.1 — between genes, 10.7 kb from ZNF655.

What each result means

G/G No copy of the version the research linked to Androsterone sulfate-to-4-androsten-3beta,17beta-diol disulfate 2 ratio. This is the starting point the study compared everyone against.
G/T One copy of the version the research linked to Androsterone sulfate-to-4-androsten-3beta,17beta-diol disulfate 2 ratio. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Androsterone sulfate-to-4-androsten-3beta,17beta-diol disulfate 2 ratio. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs7809615

What is rs7809615?

rs7809615 is a single position in the genome, in or near the near ZNF655 gene. Published research associates it with androsterone sulfate-to-4-androsten-3beta,17beta-diol disulfate 2 ratio. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs7809615 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs7809615 come from?

GWAS Catalog, Nature genetics 2014, PMID:24816252. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Androsterone sulfate-to-4-androsten-3beta,17beta-diol disulfate 2 ratio (rs7809615). MyGeneLog™. https://www.mygenelog.com/variants/rs7809615

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