Sensitive

Systemic lupus erythematosus

SLC29A3 · rs780669

Where this position leads

Condition: Systemic Lupus Erythematosus

rs780669 Condition: Systemic Lupus Erythematosus Systemic Lupus Erythematosus Condition rs780669 rs780669 SLC29A3

What the study found

Who was studied 4,734 Chinese ancestry cases, 9,425 Chinese ancestry controls, 835 Thai ancestry cases, 2,995 Thai ancestry controls.

The effect Each copy of the T allele carried 1.16 times the odds of Systemic lupus erythematosus (95% confidence interval 1.1-1.22); p = 5 × 10−9.

How common The T allele had a frequency of about 65% in the people studied.

Where it sits Chromosome 10, band 10q22.1 — in an intron of SLC29A3.

What each result means

C/C No copy of the version the research linked to Systemic lupus erythematosus. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Systemic lupus erythematosus. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Systemic lupus erythematosus. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs780669

What is rs780669?

rs780669 is a single position in the genome, in or near the SLC29A3 gene. Published research associates it with systemic lupus erythematosus. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs780669 linked to?

On MyGeneLog this position is linked to Systemic Lupus Erythematosus. The research behind each link, and its sources, are set out on that condition page.

Does having rs780669 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs780669 come from?

GWAS Catalog, Arthritis & rheumatology (Hoboken, N.J.) 2022, PMID:34783190. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Systemic lupus erythematosus (rs780669). MyGeneLog™. https://www.mygenelog.com/variants/rs780669

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