Sensitive

Lung cancer or family history of lung cancer

ADAR · rs78062588

Where this position leads

Condition: Lung Cancer

rs78062588 Condition: Lung Cancer Lung Cancer Condition rs78062588 rs78062588 ADAR

What the study found

Who was studied 29,266 European ancestry lung cancer cases, 48,843 European ancestry individuals with family history of lung cancer, 251,837 European ancestry controls.

The effect Each copy of the C allele carried 0.90 times the odds of Lung cancer or family history of lung cancer (95% confidence interval 0.868-0.94); p = 4 × 10−8.

How common The C allele had a frequency of about 7% in the people studied.

Where it sits Chromosome 1, band 1q21.3 — in an intron of ADAR.

What each result means

C/C Two copies of the version the research linked to Lung cancer or family history of lung cancer. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Lung cancer or family history of lung cancer. That is a smaller link than two copies.
T/T No copy of the version the research linked to Lung cancer or family history of lung cancer. This is the starting point the study compared everyone against.
Source

Questions about rs78062588

What is rs78062588?

rs78062588 is a single position in the genome, in or near the ADAR gene. Published research associates it with lung cancer or family history of lung cancer. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs78062588 linked to?

On MyGeneLog this position is linked to Lung Cancer. The research behind each link, and its sources, are set out on that condition page.

Does having rs78062588 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs78062588 come from?

GWAS Catalog, Journal of the National Cancer Institute 2022, PMID:35511172. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Lung cancer or family history of lung cancer (rs78062588). MyGeneLog™. https://www.mygenelog.com/variants/rs78062588

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