Standard

Glucosuria

HNF1A · rs780518365

What the study found

Who was studied 10,857 Icelandic ancestry cases, 135,512 Icelandic ancestry controls (includes non-array genotyped, whole-genome imputed individuals).

The effect Each copy of the G allele carried 7.05 times the odds of Glucosuria (95% confidence interval 3.95-12.60); p = 4 × 10−11.

How common The G allele had a frequency of about 0% in the people studied.

Where it sits Chromosome 12, band 12q24.31 — in an intron of HNF1A.

What each result means

A/A No copy of the version the research linked to Glucosuria. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Glucosuria. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Glucosuria. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs780518365

What is rs780518365?

rs780518365 is a single position in the genome, in or near the HNF1A gene. Published research associates it with glucosuria. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs780518365 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs780518365 come from?

GWAS Catalog, Human molecular genetics 2019, PMID:30476138. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Glucosuria (rs780518365). MyGeneLog™. https://www.mygenelog.com/variants/rs780518365

← See all variants