Standard

Hypertension

SLC12A9 · rs7801190

Where this position leads

Condition: Blood Pressure

rs7801190 Condition: Blood Pressure Blood Pressure Condition rs7801190 rs7801190 SLC12A9

What the study found

Who was studied 4,069 African American cases, 3,848 African American controls; replicated in 1,372 African American cases, 1,482 African American controls.

The effect Each copy of the C allele carried 1.31 times the odds of Hypertension (95% confidence interval 1.19-1.44); p = 3 × 10−8.

How common The C allele had a frequency of about 72% in the people studied.

Where it sits Chromosome 7, band 7q22.1 — in an intron of SLC12A9.

What each result means

C/C Two copies of the version the research linked to Hypertension. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/G One copy of the version the research linked to Hypertension. That is a smaller link than two copies.
G/G No copy of the version the research linked to Hypertension. This is the starting point the study compared everyone against.
Source

Questions about rs7801190

What is rs7801190?

rs7801190 is a single position in the genome, in or near the SLC12A9 gene. Published research associates it with hypertension. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs7801190 linked to?

On MyGeneLog this position is linked to Blood Pressure. The research behind each link, and its sources, are set out on that condition page.

Does having rs7801190 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs7801190 come from?

GWAS Catalog, PLoS Genet 2011, PMID:21347282. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Hypertension (rs7801190). MyGeneLog™. https://www.mygenelog.com/variants/rs7801190

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