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Uric acid levels

GCKR · rs780094

What the study found

Who was studied 12,328 European ancestry males, 15,813 European ancestry females.

The effect Each copy of the T allele shifted the measure 0.05 mg/dl higher (95% confidence interval 0.035-0.068); p = 1 × 10−9.

How common The T allele had a frequency of about 42% in the people studied.

Where it sits Chromosome 2, band 2p23.3 — in an intron of GCKR.

What each result means

C/C No copy of the version the research linked to Uric acid levels. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Uric acid levels. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Uric acid levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

What people read about alongside this

Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.

Questions about rs780094

What is rs780094?

rs780094 is a single position in the genome, in or near the GCKR gene. Published research associates it with uric acid levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What do people read about alongside rs780094?

Subjects that appear in the title or abstract of the same papers as this rsID include blood sugar and insulin (64 papers), cholesterol and blood fats (10 papers), heart and circulation (6 papers), alcohol and the flush (5 papers), liver (5 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.

Does having rs780094 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs780094 come from?

GWAS Catalog, PLoS Genet 2009, PMID:19503597. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Uric acid levels (rs780094). MyGeneLog™. https://www.mygenelog.com/variants/rs780094

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