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Leptin levels in lean individuals

near PRSS37 · rs7798566

What the study found

Who was studied 1,582 Sub-Saharan African ancestry individuals; replicated in 606 African American individuals.

The effect Each copy of the G allele shifted the measure 0.489 lower (95% confidence interval 0.38-0.6); p = 5 × 10−18.

Where it sits Chromosome 7, band 7q34 — between genes, 8 kb from PRSS37.

What each result means

A/A No copy of the version the research linked to Leptin levels in lean individuals. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Leptin levels in lean individuals. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Leptin levels in lean individuals. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs7798566

What is rs7798566?

rs7798566 is a single position in the genome, in or near the near PRSS37 gene. Published research associates it with leptin levels in lean individuals. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs7798566 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs7798566 come from?

GWAS Catalog, Genome medicine 2021, PMID:34620218. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Leptin levels in lean individuals (rs7798566). MyGeneLog™. https://www.mygenelog.com/variants/rs7798566

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