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PRG3 protein levels

CCDC26 · rs77959102

What the study found

Who was studied 47,745 European ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.0951 lower (95% confidence interval 0.079-0.111); p = 2 × 10−38.

How common The C allele had a frequency of about 15% in the people studied.

Where it sits Chromosome 8, band 8q24.21 — inside CCDC26.

What each result means

C/C Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of PRG3 protein levels compared to the general population.
C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with PRG3 protein levels.
T/T Published research associates this genotype with typical/baseline likelihood of PRG3 protein levels — no copies of the reported risk allele.
Source

Questions about rs77959102

What is rs77959102?

rs77959102 is a single position in the genome, in or near the CCDC26 gene. Published research associates it with prg3 protein levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs77959102 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs77959102 come from?

GWAS Catalog, Nature genetics 2025, PMID:39789286. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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PRG3 protein levels (rs77959102). MyGeneLog™. https://www.mygenelog.com/variants/rs77959102

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