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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 48,997 European ancestry individuals, 958 Asian ancestry individuals, 745 African ancestry individuals.
The effect
Each copy of the C allele shifted the measure 0.0533 lower; p = 1 × 10−8.
How common The C allele had a frequency of about 49% in the people studied.
Where it sits Chromosome 8, band 8p23.1 — in an intron of MFHAS1.
What each result means
A/ANo copy of the version the research linked to Grade of retinal pigmentation. This is the starting point the study compared everyone against.
A/COne copy of the version the research linked to Grade of retinal pigmentation. That is a smaller link than two copies.
C/CTwo copies of the version the research linked to Grade of retinal pigmentation. That is the strongest link of the three results. A link in a study is not a diagnosis.
Science advances · 2026 · PMID 41477839 · open access
Questions about rs77915629
What is rs77915629?
rs77915629 is a single position in the genome, in or near the MFHAS1 gene. Published research associates it with grade of retinal pigmentation. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs77915629 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs77915629 come from?
GWAS Catalog, Science advances 2026, PMID:41477839. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Grade of retinal pigmentation (rs77915629). MyGeneLog™. https://www.mygenelog.com/variants/rs77915629