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Atrial fibrillation

ZNF385D · rs779029

Where this position leads

Condition: Atrial Fibrillation

rs779029 Condition: Atrial Fibrillation Atrial Fibrillation Condition rs779029 rs779029 ZNF385D

What the study found

Who was studied 1,782 Admix African and African American ancestry cases, 9,356 Admix African and African American ancestry controls, 11,350 East Asian ancestry cases, 137,515 East Asian ancestry controls, 166,322 European ancestry cases, 1,313,950 European ancestry controls, 1,774 Hispanic or Latin American cases, 7,665 Hispanic or Latin American controls, 218 South Asian ancestry cases, 413 South Asian ancestry controls.

The effect Each copy of the A allele carried 1.03 times the odds of Atrial fibrillation (95% confidence interval 1.02-1.04); p = 1 × 10−8.

How common The A allele had a frequency of about 76% in the people studied.

Where it sits Chromosome 3, band 3p24.3 — in an intron of ZNF385D.

What each result means

A/A Two copies of the version the research linked to Atrial fibrillation. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/C One copy of the version the research linked to Atrial fibrillation. That is a smaller link than two copies.
C/C No copy of the version the research linked to Atrial fibrillation. This is the starting point the study compared everyone against.
Source

Questions about rs779029

What is rs779029?

rs779029 is a single position in the genome, in or near the ZNF385D gene. Published research associates it with atrial fibrillation. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs779029 linked to?

On MyGeneLog this position is linked to Atrial Fibrillation. The research behind each link, and its sources, are set out on that condition page.

Does having rs779029 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs779029 come from?

GWAS Catalog, Nature genetics 2025, PMID:40050429. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Atrial fibrillation (rs779029). MyGeneLog™. https://www.mygenelog.com/variants/rs779029

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