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Serum 25-Hydroxyvitamin D levels (conditioned on BMI)

ZNF680 · rs7784802

What the study found

Who was studied 417,580 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.014 higher (95% confidence interval 0.01-0.018); p = 1 × 10−11.

How common The A allele had a frequency of about 64% in the people studied.

Where it sits Chromosome 7, band 7q11.21 — in an intron of ZNF680.

What each result means

A/A Two copies of the version the research linked to Serum 25-Hydroxyvitamin D levels (conditioned on BMI). That is the strongest link of the three results. A link in a study is not a diagnosis.
A/T One copy of the version the research linked to Serum 25-Hydroxyvitamin D levels (conditioned on BMI). That is a smaller link than two copies.
T/T No copy of the version the research linked to Serum 25-Hydroxyvitamin D levels (conditioned on BMI). This is the starting point the study compared everyone against.
Source

Questions about rs7784802

What is rs7784802?

rs7784802 is a single position in the genome, in or near the ZNF680 gene. Published research associates it with serum 25-hydroxyvitamin d levels (conditioned on bmi). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs7784802 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs7784802 come from?

GWAS Catalog, Nature communications 2020, PMID:32242144. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Serum 25-Hydroxyvitamin D levels (conditioned on BMI) (rs7784802). MyGeneLog™. https://www.mygenelog.com/variants/rs7784802

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