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Who was studied 6,337 European ancestry cases, 61,607 European ancestry controls; replicated in 30,679 European ancestry cases, 278,895 European ancestry controls.
The effect
Each copy of the T allele carried 1.41 times the odds of Atrial fibrillation (95% confidence interval 1.34-1.48); p = 2 × 10−39.
How common The T allele had a frequency of about 18% in the people studied.
Where it sits Chromosome 4, band 4q25 — between genes, 1.2 kb from LINC01438.
What each result means
G/GNo copy of the version the research linked to Atrial fibrillation. This is the starting point the study compared everyone against.
G/TOne copy of the version the research linked to Atrial fibrillation. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Atrial fibrillation. That is the strongest link of the three results. A link in a study is not a diagnosis.
American journal of human genetics · 2018 · PMID 29290336
Questions about rs77831929
What is rs77831929?
rs77831929 is a single position in the genome, in or near the PITX2 gene. Published research associates it with atrial fibrillation. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs77831929 linked to?
On MyGeneLog this position is linked to Atrial Fibrillation. The research behind each link, and its sources, are set out on that condition page.
Does having rs77831929 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs77831929 come from?
GWAS Catalog, Am J Hum Genet 2018, PMID:29290336. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 4932228223223Reads by AI crawlersClaude3ChatGPT2Google · Gemini2Perplexity2Meta AI8Microsoft · Copilot2Amazon2Apple3China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others23Total49Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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