Sensitive

Breast cancer subtype (triple negative vs luminal A-like)

NR2F6 · rs77825513

Where this position leads

Condition: Breast Cancer

rs77825513 Condition: Breast Cancer Breast Cancer Condition rs77825513 rs77825513 NR2F6

What the study found

Who was studied 16,499 European ancestry triple negative cases, 60,715 European ancestry luminal A-like cases.

The effect Each copy of the A allele shifted the measure 0.022 higher (95% confidence interval 0.014-0.03); p = 1 × 10−9.

Where it sits Chromosome 19, band 19p13.11 — in an intron of NR2F6.

What each result means

A/A Two copies of the version the research linked to Breast cancer subtype (triple negative vs luminal A-like). That is the strongest link of the three results. A link in a study is not a diagnosis.
A/C One copy of the version the research linked to Breast cancer subtype (triple negative vs luminal A-like). That is a smaller link than two copies.
C/C No copy of the version the research linked to Breast cancer subtype (triple negative vs luminal A-like). This is the starting point the study compared everyone against.
Source

Questions about rs77825513

What is rs77825513?

rs77825513 is a single position in the genome, in or near the NR2F6 gene. Published research associates it with breast cancer subtype (triple negative vs luminal a-like). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs77825513 linked to?

On MyGeneLog this position is linked to Breast Cancer. The research behind each link, and its sources, are set out on that condition page.

Does having rs77825513 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs77825513 come from?

GWAS Catalog, Cancer research 2024, PMID:38832928. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Breast cancer subtype (triple negative vs luminal A-like) (rs77825513). MyGeneLog™. https://www.mygenelog.com/variants/rs77825513

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