Sensitive

Systemic lupus erythematosus

AHCYL2 · rs7781902

Where this position leads

Condition: Systemic Lupus Erythematosus

Drug: Fenofibrate

rs7781902 Condition: Systemic Lupus Erythematosus Systemic Lupus Erythematosus Condition Drug: Fenofibrate Fenofibrate Drug rs7781902 rs7781902 AHCYL2

What the study found

Who was studied 16,491 European ancestry cases, 1,202,106 European ancestry controls, 5,051 East Asian ancestry cases, 185,362 East Asian ancestry controls, 740 African American or Afro-Caribbean cases, 120,993 African American or Afro-Caribbean controls, 212 Hispanic or Latin American cases, 59,641 Hispanic or Latin American controls.

The effect Each copy of the T allele shifted the measure 0.22 higher (95% confidence interval 0.1-0.34); p = 5 × 10−9.

What each result means

C/C No copy of the version the research linked to Systemic lupus erythematosus. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Systemic lupus erythematosus. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Systemic lupus erythematosus. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs7781902

What is rs7781902?

rs7781902 is a single position in the genome, in or near the AHCYL2 gene. Published research associates it with systemic lupus erythematosus. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs7781902 linked to?

On MyGeneLog this position is linked to Systemic Lupus Erythematosus. The research behind each link, and its sources, are set out on that condition page.

Does rs7781902 affect how medicines work?

AHCYL2 carries pharmacogenomic findings for Fenofibrate. That is educational information, not a prescription or a dosing guide. Any decision to start, stop or change a medicine belongs with the clinician or pharmacist managing your treatment.

Does having rs7781902 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs7781902 come from?

GWAS Catalog, Mammalian genome : official journal of the International Mammalian Genome Society 2026, PMID:42581184. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Systemic lupus erythematosus (rs7781902). MyGeneLog™. https://www.mygenelog.com/variants/rs7781902

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