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Left–right brain asymmetry

TUBB · rs7781

What the study found

Who was studied 32,256 European ancestry individuals.

The effect The reported allele is G; the catalogue records no effect size ; p = 2 × 10−10.

How common The G allele had a frequency of about 24% in the people studied.

Where it sits Chromosome 6, band 6p21.33 — in the 3′ untranslated region of TUBB.

What each result means

A/A No copy of the version the research linked to Left–right brain asymmetry. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Left–right brain asymmetry. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Left–right brain asymmetry. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs7781

What is rs7781?

rs7781 is a single position in the genome, in or near the TUBB gene. Published research associates it with left–right brain asymmetry. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs7781 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs7781 come from?

GWAS Catalog, Nature human behaviour 2021, PMID:33723403. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Left–right brain asymmetry (rs7781). MyGeneLog™. https://www.mygenelog.com/variants/rs7781

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