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Who was studied 29,212 European ancestry cases, 400,539 European ancestry controls, 4,150 East Asian ancestry cases, 155,540 East Asian ancestry controls.
The effect
Each copy of the G allele shifted the measure 0.0574 lower (95% confidence interval 0.038-0.076); p = 4 × 10−9.
Where it sits Chromosome X, band Xq24 — between genes, 4.8 kb from SEPTIN6.
What each result means
A/ANo copy of the version the research linked to Atrial fibrillation/atrial flutter. This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to Atrial fibrillation/atrial flutter. That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Atrial fibrillation/atrial flutter. That is the strongest link of the three results. A link in a study is not a diagnosis.
rs77806999 is a single position in the genome, in or near the near SEPTIN6 gene. Published research associates it with atrial fibrillation/atrial flutter. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs77806999 linked to?
On MyGeneLog this position is linked to Atrial Fibrillation. The research behind each link, and its sources, are set out on that condition page.
Does having rs77806999 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs77806999 come from?
GWAS Catalog, Nature genetics 2021, PMID:34594039. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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