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Male-pattern baldness

RSPO2 · rs77767830

Where this position leads

Condition: Androgenetic Alopecia (Male Pattern Baldness)

rs77767830 Condition: Androgenetic Alopecia (Male Pattern Baldness) Androgenetic Alopecia (Male Pattern… Condition rs77767830 rs77767830 RSPO2

What the study found

Who was studied 25,662 British ancestry cases, 17,928 British ancestry controls; replicated in 13,367 European ancestry cases, 11,851 European ancestry controls, 3,436 cases, 2,435 controls.

The effect Each copy of the A allele shifted the measure 0.311 higher (95% confidence interval 0.23-0.39); p = 2 × 10−14.

Where it sits Chromosome 8, band 8q23.1 — inside EIF3E.

What each result means

A/A Two copies of the version the research linked to Male-pattern baldness. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/T One copy of the version the research linked to Male-pattern baldness. That is a smaller link than two copies.
T/T No copy of the version the research linked to Male-pattern baldness. This is the starting point the study compared everyone against.
Source

Questions about rs77767830

What is rs77767830?

rs77767830 is a single position in the genome, in or near the RSPO2 gene. Published research associates it with male-pattern baldness. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs77767830 linked to?

On MyGeneLog this position is linked to Androgenetic Alopecia (Male Pattern Baldness). The research behind each link, and its sources, are set out on that condition page.

Does having rs77767830 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs77767830 come from?

GWAS Catalog, Nat Commun 2017, PMID:29146897. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Male-pattern baldness (rs77767830). MyGeneLog™. https://www.mygenelog.com/variants/rs77767830

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