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Idiopathic membranous nephropathy

c6orf10 · rs7775397

Where this position leads

Condition: Idiopathic Membranous Nephropathy

rs7775397 Condition: Idiopathic Membranous Nephropathy Idiopathic Membranous Nephropathy Condition rs7775397 rs7775397 c6orf10

What the study found

Who was studied 556 European ancestry cases, 2,338 European ancestry controls.

The effect Each copy of the G allele carried 3.83 times the odds of Idiopathic membranous nephropathy; p = 5 × 10−71.

How common The G allele had a frequency of about 11% in the people studied.

Where it sits Chromosome 6, band 6p21.32 — a missense change in TSBP1.

What each result means

G/G Two copies of the version the research linked to Idiopathic membranous nephropathy. That is the strongest link of the three results. A link in a study is not a diagnosis.
G/T One copy of the version the research linked to Idiopathic membranous nephropathy. That is a smaller link than two copies.
T/T No copy of the version the research linked to Idiopathic membranous nephropathy. This is the starting point the study compared everyone against.
Source

Questions about rs7775397

What is rs7775397?

rs7775397 is a single position in the genome, in or near the c6orf10 gene. Published research associates it with idiopathic membranous nephropathy. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs7775397 linked to?

On MyGeneLog this position is linked to Idiopathic Membranous Nephropathy. The research behind each link, and its sources, are set out on that condition page.

Does having rs7775397 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs7775397 come from?

GWAS Catalog, The New England journal of medicine 2011, PMID:21323541. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Idiopathic membranous nephropathy (rs7775397). MyGeneLog™. https://www.mygenelog.com/variants/rs7775397

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