Sensitive

Post-traumatic stress disorder (phenotype risk score)

VRK2 · rs77736916

What the study found

Who was studied 497,803 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.0344 higher (95% confidence interval 0.022-0.046); p = 2 × 10−8.

Where it sits Chromosome 2, band 2p16.1 — in an intron of VRK2.

What each result means

A/A Two copies of the version the research linked to Post-traumatic stress disorder (phenotype risk score). That is the strongest link of the three results. A link in a study is not a diagnosis.
A/T One copy of the version the research linked to Post-traumatic stress disorder (phenotype risk score). That is a smaller link than two copies.
T/T No copy of the version the research linked to Post-traumatic stress disorder (phenotype risk score). This is the starting point the study compared everyone against.
Source

Questions about rs77736916

What is rs77736916?

rs77736916 is a single position in the genome, in or near the VRK2 gene. Published research associates it with post-traumatic stress disorder (phenotype risk score). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs77736916 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs77736916 come from?

GWAS Catalog, Molecular psychiatry 2022, PMID:35181757. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Post-traumatic stress disorder (phenotype risk score) (rs77736916). MyGeneLog™. https://www.mygenelog.com/variants/rs77736916

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