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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 34,552 European ancestry individuals.
The effect
The reported allele is A; the catalogue records no effect size
; p = 6 × 10−13.
Where it sits Chromosome 8, band 8p21.2 — in an intron of PPP2R2A.
What each result means
A/ATwo copies of the version the research linked to Global cortical thickness (GlobalMeanMean). That is the strongest link of the three results. A link in a study is not a diagnosis.
A/TOne copy of the version the research linked to Global cortical thickness (GlobalMeanMean). That is a smaller link than two copies.
T/TNo copy of the version the research linked to Global cortical thickness (GlobalMeanMean). This is the starting point the study compared everyone against.
Nature communications · 2024 · PMID 38890310 · open access
Questions about rs77690628
What is rs77690628?
rs77690628 is a single position in the genome, in or near the PPP2R2A gene. Published research associates it with global cortical thickness (globalmeanmean). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs77690628 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs77690628 come from?
GWAS Catalog, Nature communications 2024, PMID:38890310. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Global cortical thickness (GlobalMeanMean) (rs77690628). MyGeneLog™. https://www.mygenelog.com/variants/rs77690628