Standard

HDL cholesterol levels

HCG27 · rs7769059

What the study found

Who was studied 403,943 European ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.0151 higher (95% confidence interval 0.011-0.019); p = 1 × 10−12.

How common The G allele had a frequency of about 72% in the people studied.

Where it sits Chromosome 6, band 6p21.33 — between genes, 16.5 kb from HCG27.

What each result means

A/A No copy of the version the research linked to HDL cholesterol levels. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to HDL cholesterol levels. That is a smaller link than two copies.
G/G Two copies of the version the research linked to HDL cholesterol levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs7769059

What is rs7769059?

rs7769059 is a single position in the genome, in or near the HCG27 gene. Published research associates it with hdl cholesterol levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs7769059 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs7769059 come from?

GWAS Catalog, PLoS medicine 2020, PMID:32203549. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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HDL cholesterol levels (rs7769059). MyGeneLog™. https://www.mygenelog.com/variants/rs7769059

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