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Sleep start time

MIR129-2 · rs77677460

What the study found

Who was studied 90,515 individuals.

The effect Each copy of the G allele shifted the measure 0.471 higher (95% confidence interval 0.31-0.63); p = 1 × 10−8.

Where it sits Chromosome 11, band 11p11.2 — in an intron of MIR670HG.

What each result means

C/C Published research associates this genotype with typical/baseline likelihood of Sleep start time — no copies of the reported risk allele.
C/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Sleep start time.
G/G Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Sleep start time compared to the general population.
Source

Questions about rs77677460

What is rs77677460?

rs77677460 is a single position in the genome, in or near the MIR129-2 gene. Published research associates it with sleep start time. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs77677460 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs77677460 come from?

GWAS Catalog, PLoS Genet 2020, PMID:33075057. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Sleep start time (rs77677460). MyGeneLog™. https://www.mygenelog.com/variants/rs77677460

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