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Serum metabolite levels

C9orf91 · rs77654326

What the study found

Who was studied 3,926 Hispanic/Latino individuals.

The effect Each copy of the G allele shifted the measure 0.27 higher (95% confidence interval 0.21-0.33); p = 5 × 10−17.

How common The G allele had a frequency of about 85% in the people studied.

Where it sits Chromosome 9, band 9q32 — in an intron of TMEM268.

What each result means

G/G Two copies of the version the research linked to Serum metabolite levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
G/T One copy of the version the research linked to Serum metabolite levels. That is a smaller link than two copies.
T/T No copy of the version the research linked to Serum metabolite levels. This is the starting point the study compared everyone against.
Source

Questions about rs77654326

What is rs77654326?

rs77654326 is a single position in the genome, in or near the C9orf91 gene. Published research associates it with serum metabolite levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs77654326 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs77654326 come from?

GWAS Catalog, American journal of human genetics 2020, PMID:33031748. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Serum metabolite levels (rs77654326). MyGeneLog™. https://www.mygenelog.com/variants/rs77654326

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