Sensitive

Crohn's disease

HLA-DQA2 · rs7765379

Where this position leads

Condition: Crohn's Disease

rs7765379 Condition: Crohn's Disease Crohn's Disease Condition rs7765379 rs7765379 HLA-DQA2

What the study found

Who was studied 372 Japanese ancestry cases,3,389 Japanese ancestry controls; replicated in Up to 1,151 Japanese ancestry cases, up to 15,800 Japanese ancestry controls.

The effect Each copy of the G allele carried 1.93 times the odds of Crohn's disease (95% confidence interval 1.78-2.09); p = 9 × 10−59.

Where it sits Chromosome 6, band 6p21.32 — between genes, 4.9 kb from LOC102725019.

What each result means

G/G Two copies of the version the research linked to Crohn's disease. That is the strongest link of the three results. A link in a study is not a diagnosis.
G/T One copy of the version the research linked to Crohn's disease. That is a smaller link than two copies.
T/T No copy of the version the research linked to Crohn's disease. This is the starting point the study compared everyone against.
Source

What people read about alongside this

Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.

Questions about rs7765379

What is rs7765379?

rs7765379 is a single position in the genome, in or near the HLA-DQA2 gene. Published research associates it with crohn's disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs7765379 linked to?

On MyGeneLog this position is linked to Crohn's Disease. The research behind each link, and its sources, are set out on that condition page.

What do people read about alongside rs7765379?

Subjects that appear in the title or abstract of the same papers as this rsID include infection and immunity (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.

Does having rs7765379 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs7765379 come from?

GWAS Catalog, Gastroenterology 2012, PMID:23266558. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Crohn's disease (rs7765379). MyGeneLog™. https://www.mygenelog.com/variants/rs7765379

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