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Macrocytic percentage of red cells

near RNF182 · rs7761500

What the study found

Who was studied 37,432 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.0946 SD units lower (95% confidence interval 0.08-0.109); p = 2 × 10−36.

How common The A allele had a frequency of about 36% in the people studied.

Where it sits Chromosome 6, band 6p23 — between genes, 7.5 kb from RNF182.

What each result means

A/A Two copies of the version the research linked to Macrocytic percentage of red cells. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Macrocytic percentage of red cells. That is a smaller link than two copies.
G/G No copy of the version the research linked to Macrocytic percentage of red cells. This is the starting point the study compared everyone against.
Source

Questions about rs7761500

What is rs7761500?

rs7761500 is a single position in the genome, in or near the near RNF182 gene. Published research associates it with macrocytic percentage of red cells. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs7761500 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs7761500 come from?

GWAS Catalog, Nature communications 2023, PMID:37596262. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Macrocytic percentage of red cells (rs7761500). MyGeneLog™. https://www.mygenelog.com/variants/rs7761500

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