Cough in response to angiotensin-converting enzyme inhibitor drugs
PREP · rs7761208
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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 226 African ancestry cases, 1,061 African ancestry controls, 20,197 European ancestry cases, 53,566 European ancestry controls, 32 East Asian ancestry cases, 116 East Asian ancestry controls, 997 South Asian ancestry cases, 7,703 South Asian ancestry controls, 71 cases, 123 controls.
The effect
Each copy of the T allele carried 0.86 times the odds of Cough in response to angiotensin-converting enzyme inhibitor drugs (95% confidence interval 0.84-0.89); p = 4 × 10−21.
How common The T allele had a frequency of about 78% in the people studied.
Where it sits Chromosome 6, band 6q21 — in an intron of PREP.
What each result means
C/CNo copy of the version the research linked to Cough in response to angiotensin-converting enzyme inhibitor drugs. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Cough in response to angiotensin-converting enzyme inhibitor drugs. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Cough in response to angiotensin-converting enzyme inhibitor drugs. That is the strongest link of the three results. A link in a study is not a diagnosis.
The European respiratory journal · 2025 · PMID 40675770 · open access
Questions about rs7761208
What is rs7761208?
rs7761208 is a single position in the genome, in or near the PREP gene. Published research associates it with cough in response to angiotensin-converting enzyme inhibitor drugs. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs7761208 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs7761208 come from?
GWAS Catalog, The European respiratory journal 2025, PMID:40675770. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 10226Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple2China (ByteDance, Huawei, Baidu…)0Others6Total10Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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Cough in response to angiotensin-converting enzyme inhibitor drugs (rs7761208). MyGeneLog™. https://www.mygenelog.com/variants/rs7761208