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Cholesteryl esters in chylomicrons and extremely large VLDL (UKB data field 23485)

near HLA-DRB1 · rs7757916

What the study found

Who was studied 88,329 European ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.0864 higher (95% confidence interval 0.06-0.113); p = 1 × 10−10.

How common The C allele had a frequency of about 4% in the people studied.

Where it sits Chromosome 6, band 6p21.32 — between genes, 0.7 kb from HLA-DRB1.

What each result means

C/C Two copies of the version the research linked to Cholesteryl esters in chylomicrons and extremely large VLDL (UKB data field 23485). That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Cholesteryl esters in chylomicrons and extremely large VLDL (UKB data field 23485). That is a smaller link than two copies.
T/T No copy of the version the research linked to Cholesteryl esters in chylomicrons and extremely large VLDL (UKB data field 23485). This is the starting point the study compared everyone against.
Source

Questions about rs7757916

What is rs7757916?

rs7757916 is a single position in the genome, in or near the near HLA-DRB1 gene. Published research associates it with cholesteryl esters in chylomicrons and extremely large vldl (ukb data field 23485). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs7757916 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs7757916 come from?

GWAS Catalog, Biological psychiatry 2023, PMID:36764567. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Cholesteryl esters in chylomicrons and extremely large VLDL (UKB data field 23485) (rs7757916). MyGeneLog™. https://www.mygenelog.com/variants/rs7757916

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