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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 650 Amish individuals; replicated in 847 European American ancestry individuals.
The effect
Each copy of the G allele shifted the measure 0.376 lower; p = 4 × 10−10.
How common The G allele had a frequency of about 36% in the people studied.
Where it sits Chromosome 20, band 20p12.1 — in an intron of KIF16B.
What each result means
A/ANo copy of the version the research linked to Ceramide (d43:1) levels. This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to Ceramide (d43:1) levels. That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Ceramide (d43:1) levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Communications biology · 2022 · PMID 35393526 · open access
Questions about rs77552380
What is rs77552380?
rs77552380 is a single position in the genome, in or near the KIF16B gene. Published research associates it with ceramide (d43:1) levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs77552380 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs77552380 come from?
GWAS Catalog, Communications biology 2022, PMID:35393526. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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