PRR5L · rs77531520
Where this position leads
Condition: Atopic Dermatitis
What the study found
Who was studied 33,262 European ancestry cases, 804,234 European ancestry controls; replicated in 7,267 East Asian ancestry cases, 219,529 East Asian ancestry controls, 2,785 African American or Afro-Caribbean cases, 3,933 African American or Afro-Caribbean controls.
The effect Each copy of the T allele shifted the measure 0.142 higher (95% confidence interval 0.1-0.18); p = 5 × 10−13.
Where it sits Chromosome 11, band 11p12 — in an intron of PRR5L.
rs77531520 is a single position in the genome, in or near the PRR5L gene. Published research associates it with atopic dermatitis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
On MyGeneLog this position is linked to Atopic Dermatitis. The research behind each link, and its sources, are set out on that condition page.
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
GWAS Catalog, The Journal of investigative dermatology 2022, PMID:35577104. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Atopic dermatitis (rs77531520). MyGeneLog™. https://www.mygenelog.com/variants/rs77531520