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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 965 European ancestry cases, 154 African American cases, 168 cases, 7,255 European ancestry controls, 1,717 African American controls, 450 controls.
The effect
Each copy of the G allele carried 1.32 times the odds of Subpleural-predominant interstitial lung abnormalities (95% confidence interval 1.19-1.45); p = 4 × 10−8.
How common The G allele had a frequency of about 28% in the people studied.
Where it sits Chromosome 6, band 6q14.3 — between genes, 11 kb from HTR1E.
What each result means
A/ANo copy of the version the research linked to Subpleural-predominant interstitial lung abnormalities. This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to Subpleural-predominant interstitial lung abnormalities. That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Subpleural-predominant interstitial lung abnormalities. That is the strongest link of the three results. A link in a study is not a diagnosis.
American journal of respiratory and critical care medicine · 2019 · PMID 31339356
Questions about rs7744971
What is rs7744971?
rs7744971 is a single position in the genome, in or near the HTR1E gene. Published research associates it with subpleural-predominant interstitial lung abnormalities. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs7744971 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs7744971 come from?
GWAS Catalog, American journal of respiratory and critical care medicine 2019, PMID:31339356. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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