Standard

Diastolic blood pressure

PDE10A · rs7744902

Where this position leads

Condition: Blood Pressure

rs7744902 Condition: Blood Pressure Blood Pressure Condition rs7744902 rs7744902 PDE10A

What the study found

Who was studied 526,001 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.293 lower (95% confidence interval 0.21-0.37); p = 1 × 10−12.

Where it sits Chromosome 6, band 6q27 — in an intron of PDE10A.

What each result means

A/A Two copies of the version the research linked to Diastolic blood pressure. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Diastolic blood pressure. That is a smaller link than two copies.
G/G No copy of the version the research linked to Diastolic blood pressure. This is the starting point the study compared everyone against.
Source

Questions about rs7744902

What is rs7744902?

rs7744902 is a single position in the genome, in or near the PDE10A gene. Published research associates it with diastolic blood pressure. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs7744902 linked to?

On MyGeneLog this position is linked to Blood Pressure. The research behind each link, and its sources, are set out on that condition page.

Does having rs7744902 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs7744902 come from?

GWAS Catalog, Investigative ophthalmology & visual science 2022, PMID:35762941. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Diastolic blood pressure (rs7744902). MyGeneLog™. https://www.mygenelog.com/variants/rs7744902

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