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Migraine headaches

FHL5 · rs7741683

Where this position leads

Condition: Migraine

rs7741683 Condition: Migraine Migraine Condition rs7741683 rs7741683 FHL5

What the study found

Who was studied 6,952 African American or Afro-Caribbean cases, 48,553 African American or Afro-Caribbean controls, 3,724 Hispanic or Latin American cases, 25,590 Hispanic or Latin American controls, 420 East Asian ancestry cases, 3,127 East Asian ancestry controls, 28,635 European ancestry cases, 287,033 European ancestry controls.

The effect Each copy of the A allele shifted the measure 0.061 lower (95% confidence interval 0.045-0.077); p = 4 × 10−12.

How common The A allele had a frequency of about 64% in the people studied.

Where it sits Chromosome 6, band 6q16.1 — in an intron of FHL5.

What each result means

A/A Two copies of the version the research linked to Migraine headaches. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Migraine headaches. That is a smaller link than two copies.
G/G No copy of the version the research linked to Migraine headaches. This is the starting point the study compared everyone against.
Source

Questions about rs7741683

What is rs7741683?

rs7741683 is a single position in the genome, in or near the FHL5 gene. Published research associates it with migraine headaches. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs7741683 linked to?

On MyGeneLog this position is linked to Migraine. The research behind each link, and its sources, are set out on that condition page.

Does having rs7741683 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs7741683 come from?

GWAS Catalog, Science (New York, N.Y.) 2024, PMID:39024449. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Migraine headaches (rs7741683). MyGeneLog™. https://www.mygenelog.com/variants/rs7741683

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