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DXA-Bone mineral density (total body) (UKB data field 23236)

near ESR1 · rs7740042

What the study found

Who was studied 31,986 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.087 lower (95% confidence interval 0.067-0.107); p = 8 × 10−18.

How common The A allele had a frequency of about 21% in the people studied.

Where it sits Chromosome 6, band 6q25.1 — between genes, 0.7 kb from ESR1.

What each result means

A/A Two copies of the version the research linked to DXA-Bone mineral density (total body) (UKB data field 23236). That is the strongest link of the three results. A link in a study is not a diagnosis.
A/T One copy of the version the research linked to DXA-Bone mineral density (total body) (UKB data field 23236). That is a smaller link than two copies.
T/T No copy of the version the research linked to DXA-Bone mineral density (total body) (UKB data field 23236). This is the starting point the study compared everyone against.
Source

Questions about rs7740042

What is rs7740042?

rs7740042 is a single position in the genome, in or near the near ESR1 gene. Published research associates it with dxa-bone mineral density (total body) (ukb data field 23236). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs7740042 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs7740042 come from?

GWAS Catalog, Genomics, proteomics & bioinformatics 2025, PMID:41206123. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

DXA-Bone mineral density (total body) (UKB data field 23236) (rs7740042). MyGeneLog™. https://www.mygenelog.com/variants/rs7740042

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