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Platelet reactivity in response to PAR-4

F2RL3 · rs773902

What the study found

Who was studied 550 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.515 SD higher (95% confidence interval 0.38-0.65); p = 2 × 10−13.

How common The A allele had a frequency of about 20% in the people studied.

Where it sits Chromosome 19, band 19p13.11 — a missense change in F2RL3.

What each result means

A/A Two copies of the version the research linked to Platelet reactivity in response to PAR-4. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Platelet reactivity in response to PAR-4. That is a smaller link than two copies.
G/G No copy of the version the research linked to Platelet reactivity in response to PAR-4. This is the starting point the study compared everyone against.
Source

Questions about rs773902

What is rs773902?

rs773902 is a single position in the genome, in or near the F2RL3 gene. Published research associates it with platelet reactivity in response to par-4. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs773902 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs773902 come from?

GWAS Catalog, Blood advances 2022, PMID:34581777. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Platelet reactivity in response to PAR-4 (rs773902). MyGeneLog™. https://www.mygenelog.com/variants/rs773902

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